A new study demonstrates that customized DNA sequencing panels can sensitively monitor treatment response in childhood rhabdomyosarcoma. The research shows circulating tumor DNA levels correlate with disease burden and can predict relapse months before clinical detection.
Breakthrough in Pediatric Cancer Monitoring
Researchers have developed a personalized approach to tracking childhood rhabdomyosarcoma (RMS) through blood tests that detect circulating tumor DNA (ctDNA), according to a recent study published in npj Precision Oncology. The study, conducted on twelve pediatric patients, reportedly demonstrates that patient-specific sequencing panels can monitor treatment response and predict disease recurrence with high sensitivity.