Metabolic Network Study Reveals New Constraints on Biochemical Functions
Scientists have developed a framework to analyze how enforcing balance in metabolic complexes creates cascading effects throughout biochemical networks. The approach reveals universal distribution patterns across organisms and potential applications for cancer therapy.
New Framework Analyzes Metabolic Dependencies
Researchers have developed a constraint-based approach to understand how dependencies between multiple reactions impact metabolic functions, according to a recent study published in npj Systems Biology and Applications. The framework introduces the concept of “forcedly balanced complexes” to systematically explore how imposing additional balancing constraints affects metabolic networks. Sources indicate this approach could provide new ways to manipulate metabolic functions for biotechnology and therapeutic purposes.