Scientists Engineer Novel Compounds to Reprogram Cellular Signaling Pathways
Breakthrough research reveals how designed molecules can selectively steer G protein-coupled receptor signaling toward specific pathways. The findings could lead to more precise drugs with fewer side effects by controlling which cellular responses are activated.
Revolutionary Approach to Cellular Signaling
Scientists have reportedly developed a new class of compounds that can reprogram how cells respond to signals, according to research published in Nature. These engineered molecules, known as allosteric modulators, demonstrate the ability to change which G protein subtypes are activated by G protein-coupled receptors (GPCRs), potentially opening new avenues for drug development with enhanced specificity and reduced side effects.