AIScienceTechnology

Scientists Engineer Novel Compounds to Reprogram Cellular Signaling Pathways

Breakthrough research reveals how designed molecules can selectively steer G protein-coupled receptor signaling toward specific pathways. The findings could lead to more precise drugs with fewer side effects by controlling which cellular responses are activated.

Revolutionary Approach to Cellular Signaling

Scientists have reportedly developed a new class of compounds that can reprogram how cells respond to signals, according to research published in Nature. These engineered molecules, known as allosteric modulators, demonstrate the ability to change which G protein subtypes are activated by G protein-coupled receptors (GPCRs), potentially opening new avenues for drug development with enhanced specificity and reduced side effects.

AIHardwareSemiconductors

AI Industry Confronts Silent Data Corruption Crisis with Advanced Detection Methods

Silent data corruption is emerging as a critical threat to AI infrastructure reliability, with industry leaders reporting hardware errors occurring every few hours across massive server fleets. New research indicates traditional testing methods are failing to detect subtle compute-level faults that distort AI computations without triggering alerts. The industry is now turning to AI-enabled, two-stage detection systems to address this growing challenge.

The Silent Threat to AI Infrastructure

Silent data corruption (SDC) is increasingly jeopardizing the reliability of artificial intelligence systems across major technology companies, according to recent industry reports. Sources indicate that companies including Meta and Alibaba are experiencing hardware errors at alarming rates—with Meta reporting errors every three hours and Alibaba documenting 361 defective parts per million in their AI and cloud infrastructures. While these numbers might seem insignificant at smaller scales, analysts suggest they become critically important when spread across fleets containing millions of devices.